CARE Study
A Phase 1/2, Open-Label, Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity Study of Repotrectinib in Pediatric and Young Adult Subjects With Advanced or Metastatic Malignancies Harboring ALK, ROS1, NTRK1-3 Alterations
Arms / Cohorts
Phase 1:Repotrectinib (TPX-0005)
Accepting patients
Phase 2, Cohort 1:NTRK+ that are TKI naïve
Accepting patients
Phase 2, Cohort 2:NTRK+ that are TKI pre-treated
Accepting patients
Phase 2, Cohort 3:ALK/ROS1/NTRK Alterations or NTRK Fusions
Accepting patients
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