Sparrow Hospital

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TRIDENT-1

A Phase 1/2, Open-Label, Multi-Center, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of TPX-0005 in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)
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  • Tyrosine Kinase (TK) Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

TAPUR

Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer (TAPUR)
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  • ROS1 Inhibitor
  • Phase 2
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Accepting patients

ON-TRK

PrOspective Non-interventional Study in Patients With Locally Advanced or Metastatic TRK Fusion Cancer Treated With Larotrectinib
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  • Tyrosine Kinase (TK) Inhibitor

Not currently accepting

Genomically-Guided Treatment Trial in Brain Metastases
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  • PI3K Inhibitor
  • Tyrosine Kinase (TK) Inhibitor
  • CDK6
  • Phase 2