Dana-Farber Cancer Institute

Boston, MA
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Accepting patients

CARE Study

A Phase 1/2, Open-Label, Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity Study of Repotrectinib in Pediatric and Young Adult Subjects With Advanced or Metastatic Malignancies Harboring ALK, ROS1, NTRK1-3 Alterations
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  • Tyrosine Kinase (TK) Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

Larotrectinib

A Pilot and Surgical Study of Larotrectinib for Treatment of Children With Newly-Diagnosed High-Grade Glioma With NTRK Fusion
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  • Tyrosine Kinase (TK) Inhibitor
  • Phase 1
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Accepting patients

LEADER Neoadjuvant Screening Trial: LCMC4 Evaluation of Actionable Drivers in Early Stage Lung Cancers
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  • Observational Trial

Accepting patients

NAUTIKA1: Multicenter, Phase II, Neoadjuvant and Adjuvant Study of Multiple Therapies in Biomarker-Selected Patients With Resectable Stages IB-III Non-Small Cell Lung Cancer
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  • Phase 2

Not currently accepting

Genomically-Guided Treatment Trial in Brain Metastases
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  • PI3K Inhibitor
  • Tyrosine Kinase (TK) Inhibitor
  • CDK6
  • Phase 2