The Children's Hospital of Colorado

Aurora, CO
(831) 888-0898

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Accepting patients

CARE Study

A Phase 1/2, Open-Label, Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity Study of Repotrectinib in Pediatric and Young Adult Subjects With Advanced or Metastatic Malignancies Harboring ALK, ROS1, NTRK1-3 Alterations
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  • Tyrosine Kinase (TK) Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

Larotrectinib

A Pilot and Surgical Study of Larotrectinib for Treatment of Children With Newly-Diagnosed High-Grade Glioma With NTRK Fusion
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  • Tyrosine Kinase (TK) Inhibitor
  • Phase 1
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Accepting patients

NCI-COG Pediatric MATCH

NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol
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  • ALK Inhibitor
  • EphA2 Inhibitor
  • Phase 2

Accepting patients

Tumor-Agnostic Precision Immunooncology and Somatic Targeting Rational for You (TAPISTRY) Phase II Platform Trial
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  • Pan-RAF Kinase Inhibitor
  • Phase 2